In humans, the iris is a thin and circular structure in the eye, responsible for controlling the diameter and size of the pupil and thus the amount of light reaching the retina. Eye color is defined by the color of the iris.

By its functionality, the iris plays a role in the control of brightness and depth-of-field, like the diaphragm of a camera.

There are several conditions and disorders known to alter the iris and cornea functionality, increasing the light sensitivity, which has a negative effect on visual performance. Other conditions also lead to photophobia, but their origin is not related to iris dysfunctionality.

These conditions include, among others, the following ones:

Iris disorders (aniridia, coloboma), ocular albinism, high-order aberrations like keratoconus. Also, neurologic disorders where patients develop photophobia, like Chronic Migraine, Dry Eye Syndrome, or Traumatic Brain injury.

More than 25 million people worldwide suffer from high light sensitivity and iris functionality conditions.

Only in Europe, USA and Japan, more than 2 million patients could use Azalea Visions’s solution, creating a business opportunity in these regions of more than 4 billion euro per year.